Unfortunately there are situations where the body’s immune system does not function properly. Many people have an immune system which does not work well. Included are the elderly, people suffering from malnutrition, obesity, and alcoholism. Immunodeficiency can also be caused by various diseases and cancers, such as leukemia and AIDS.
Radiation treatment can cause immunodeficiency, and one dilemma in treating chronic lymphocytic leukemia (CLL) is that most of the chemotherapy agents commonly being utilized also make the body’s

“CLL affects a particular lymphocyte, the B cell, which originates in the bone marrow, develops in the lymph nodes, and normally fights infection. In CLL, the DNA of a B cell is damaged, so that it can't fight infection, but it grows out of control and crowds out the healthy blood cells that can fight infection.” Wikipedia
This picture shows a tiny little scratch which I got on the calf of my left leg several days ago. It was so small as to be almost unnoticeable. But because I have rather advanced CLL, the B cells which normally fight infection are damaged and can’t properly fight off infection.
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